Patterns of bone marrow infiltration in lymphomas- A retrospective descriptive analysis from a tertiary care centre in Southern India

Bone marrow biopsy (BMB) examination is the gold standard for staging of lymphoma which interpreted along with other clinical, laboratory and radiological investigations. This study aimed to evaluate various patterns BMB infiltration by lymphomas include Hodgkin Non usefulness compared bone aspiration (BMA). : In a period three years, there were 212 cases showed in marrow. We assessed peripheral blood smear (PBS), BMA slides concordance between each was evaluated. pattern involvement. The most frequent subtype chronic lymphocytic leukemia/small (CLL/SLL) (21.70%) followed (HL)(12.73%)and follicular (FL)(11.32%). Predominant CLL/SLL mixed pattern, FL paratrabecular mantle cell lymphoma(MCL) either diffuse or nodular, large B (DLBCL) Burkitt lymphoma(BL) predominantly pattern. Hairy leukemia (HCL) T (PTCL) an interstitial HL, usually focal nodular however involvement seen few. Of cases, 50.94% had atypical lymphocytes lymphocytosis PBS 81.14% BMA. Atypical lymphoid cells may not be present at times aspirate spite Different show characteristic